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The science behind Proto-col

With over 17 years of research and expertise in collagen supplementation, we designed our skin and body supplements with specific Bioactive Collagen Peptides®, each with a unique molecular size to target specific areas in the body:

  • Collagen Beauty Supplements to improve skin, hair, nails, and cellulite.

  • Collagen Supplements for Joints - targeting cartilage tissue.

  • Our latest innovation Complete Collagen offers twice the science to benefit both skin and connective tissues, which keep your body flexible and mobile.

How do Proto-col's collagen supplements work?

The true digestibility of the Bioactive Collagen Peptides® is 98.4%. Their unique single helix structure (a narrower shape than other collagen peptides) is absorbed almost intact by the gut cells. Their strong peptide bond is resistant to digestive enzymes that break down weaker peptide bonds. As a result, you consume more collagen and trigger your body to produce its own collagen.

The delivery format does not impact the bioavailability of our collagen supplements. Whether you prefer our collagen capsules, collagen tablets, or liquid collagen, they will work the same way.

The Bioactive Collagen Peptides® used in our supplements have been independently tested and consistently delivered strong results.

The clinical results

Clinical studies: Improved skin, hair, nails and cellulite

Improved skin, hair, nails and cellulite

When orally consumed Bioactive Collagen Peptides® (VERISOL B®) systematically effects the collagen metabolism in the dermis by stimulating the collagen producing cells (fibroblasts).

Study 1 – Increased skin elasticity

Increase in skin elasticity after 4 weeks of supplementation with 2500mg or 5000mg of VERISOL B®.

More pronounced results for women aged over 50.

Based on a double-blind study involving 69 women aged 35-55 taking a daily dose of 2500mg of VERISOL B® or 5000mg of VERISOL B® or a placebo for 4 weeks.

Study 2 - Reduced wrinkle volume

After 8 weeks of supplementation with 2500mg of VERISOL:

Based on a double-blind study involving 108 women aged 45-65 taking a daily dose of 2500mg of VERISOL B® or a placebo for 8 weeks.

Study 3 – Increase in hair thickness

In hair follicle
cell proliferation rate

In vitro tests on human follicle cells: After a 4-hour incubation period with VERSIOL®, the proliferation rate was on average 31% higher than in the untreated cells.

Changes in hair thickness after 16 weeks with VERISOL® vs. Placebo

Based on a double-blind study involving 44 healthy women aged 39-75, taking a daily dose of 2500mg of VERISOL® or a placebo for 16 weeks.

Study 4 – Improved growth and quality of nails

After 24 weeks: The growth and quality of nails improved

Based on an open, single-centre clinical trial involving 25 women aged 18-50 with common symptoms of brittle nails, taking a daily dose of 2500mg of VERISOL B® for 6 months.

Study 5 – Improvement of appearance of cellulite

11% reduction in skin waviness after 6 months of supplementation with 2500mg of VERISOL:

Clinical studies: Healthy Joints

Collagen is a protein that makes up around 30% of our total body protein, which is crucial for mobile joints, healthy bones and strong muscles, ligaments and tendons.

Through its vital role in connective tissues, collagen acts as a glue that helps hold us together.

The specific Bioactive Collagen Peptide® used in Proto-col’s joint supplements (FORTIGEL®) has been clinically tested and approved for its effects on relieving joint pain and regenerating healthy cartilage.

Study 1 – Improvement of the cartilage tissue

Change in the joint cartilage after 3 months (tissue sections*)

*Oesser S et al. (2007) Osteoarthritis Cartilage 15: C6 1-C62, 94.

Study 2 –
New generated cartilage tissue

Based on a double-blind randomised study involving 60 men and women taking a daily dose of 10,000mg of FORTIGEL® or a placebo for 48 weeks.

Study 3 – Reducing knee joint pain

Changes in exercise-induced knee pain after 12 weeks with FORTIGEL® vs. Placebo

Based on a double-blind study involving 180 men and women aged between 18-30 experiencing knee pain during and/or after exercise taking a daily dose of 5,000mg of FORTIGEL® or a placebo for 12 weeks.

Clinical studies: A flexible and mobile body

Ligaments bind bones together and tendons bind muscle to bone. Made of collagen, they are essential for movement control, stability, and better mobility.

TENDOFORTE®, the Bioactive Collagen Peptide® targets the collagen producing cells in tendons and ligaments and is designed to increase the health and quality of these crucial connecting elements of the body.

Study 3 – Reducing knee joint pain

Within 3 months, 60% of patients with chronic Achilles Tendinopathy returned to running faster.

Based on a double-blind placebo-controlled independent study involving 20 men and women with Achilles Tendinopathy aged 36 – 52 taking 2500mg of TENDOFORTE® for 12 weeks with a specialised exercise programme.